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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSSC1
All Species:
22.73
Human Site:
S189
Identified Species:
45.45
UniProt:
Q53HC9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53HC9
NP_003301.1
387
43603
S189
K
G
Q
L
K
F
T
S
G
R
W
S
P
H
H
Chimpanzee
Pan troglodytes
XP_001151736
389
43783
S191
K
G
Q
L
K
F
T
S
G
R
W
S
P
H
H
Rhesus Macaque
Macaca mulatta
XP_001098087
243
27545
H52
S
G
R
W
S
P
H
H
N
C
T
Q
V
A
T
Dog
Lupus familis
XP_532856
435
49128
S237
K
G
Q
L
K
F
T
S
G
R
W
S
P
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G5
386
43152
A189
R
G
Q
L
K
F
T
A
G
R
W
S
P
H
H
Rat
Rattus norvegicus
Q5PPK9
386
43138
S189
R
G
Q
L
K
F
T
S
G
R
W
S
P
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509323
547
60507
S349
K
G
Q
L
K
F
T
S
G
R
W
S
P
H
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3KPT3
387
43631
S189
K
G
Q
L
R
F
T
S
G
K
W
S
P
H
H
Zebra Danio
Brachydanio rerio
Q5XJP1
387
43570
A189
K
G
Q
L
K
F
T
A
G
K
W
S
P
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395260
375
42547
N179
K
G
Q
P
R
F
T
N
G
K
W
N
P
H
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780046
219
25255
Q28
N
P
H
H
N
N
S
Q
V
A
S
A
N
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22607
507
55741
E195
D
V
L
I
W
D
V
E
T
Q
P
N
R
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
62.5
82.7
N.A.
93
93.2
N.A.
61.4
N.A.
86.8
85
N.A.
N.A.
51.6
N.A.
41.6
Protein Similarity:
100
96.6
62.5
85.7
N.A.
97.6
97.4
N.A.
66.5
N.A.
95.6
95.3
N.A.
N.A.
69.2
N.A.
47
P-Site Identity:
100
100
6.6
100
N.A.
86.6
93.3
N.A.
100
N.A.
86.6
86.6
N.A.
N.A.
60
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
9
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
84
0
0
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
9
9
0
0
0
0
0
84
67
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
0
0
59
0
0
0
0
25
0
0
0
0
0
% K
% Leu:
0
0
9
67
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
9
0
9
9
0
0
17
9
0
9
% N
% Pro:
0
9
0
9
0
9
0
0
0
0
9
0
75
0
0
% P
% Gln:
0
0
75
0
0
0
0
9
0
9
0
9
0
0
0
% Q
% Arg:
17
0
9
0
17
0
0
0
0
50
0
0
9
0
0
% R
% Ser:
9
0
0
0
9
0
9
50
0
0
9
67
0
0
0
% S
% Thr:
0
0
0
0
0
0
75
0
9
0
9
0
0
0
17
% T
% Val:
0
9
0
0
0
0
9
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
9
9
0
0
0
0
0
75
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _